![]() ![]() ![]() Sections (~15/subject) taken throughout the rostral–caudal extent of the basolateral amygdala (BLA) were stained for Nissl substance and utilized for stereological estimation of volume and cell numbers. Postmortem tissues from 13 subjects with MDD and 10 controls were examined. Here, we present a stereological analysis of the volume of, and the total number of, neurons, glia, and neurovascular (pericyte and endothelial) cells in the basolateral amygdala in MDD. Neuroanatomical correlates are less clear: imaging studies have produced mixed results on amygdala volume, and postmortem neuroanatomic studies have only examined cell densities in portions of the amygdala or its subregions in MDD. ![]() Functional imaging studies consistently report abnormal amygdala activity in major depressive disorder (MDD). ![]()
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